Survival Differences in Patients with High-Flux Hemodialysis versus Expanded Hemodialysis: A Cohort Study.

ABSTRACT:

Introduction: Survival is a core outcome of hemodialysis (HD) therapy. Expanded hemodialysis (HDx) enabled by Theranova dialyzer increases clearance of medium-sized molecules and was reported to improve various patient-reported outcomes compared to HD using high-flux membranes, but the impact on survival is unclear. Herein, we evaluated the risk of death for HDx versus high-flux HD over a 4-year follow-up period.

Methods

This is a multicenter, retrospective cohort study in adult prevalent chronic HD at Renal Care Services - Colombia starting between September 1, 2017, and November 30, 2017, with follow-up for up to 4 years. The sociodemographic and clinical characteristics of all patients were summarized descriptively. The Fine-Gray subdistribution hazard model was employed to ev

SUBMITTER: Castillo JC 

PROVIDER: S-EPMC12503819 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature