Young-Onset Central Retinal Vein Occlusion with Antiphospholipid Syndrome and Hypophysitis.

ABSTRACT:

Introduction

The aim of the study was to describe a rare case of central retinal vein occlusion (CRVO) in an adolescent with primary antiphospholipid syndrome (APS) and coexisting lymphocytic hypophysitis (LH).

Case presentation

A 17-year-old female presented with acute vision loss in the right eye and was diagnosed with CRVO. She had no cardiovascular risk factors. Fundoscopy revealed optic disc swelling, macular exudates, and venous dilation. Fluorescein angiography demonstrated optic disc leakage without any signs of vasculitis. IgG anticardiolipin antibodies were persistently elevated on two separate occasions, thereby fulfilling the 2023 ACR/EULAR criteria for APS. Magnetic resonance imaging revealed pituitary stalk thickening and asymmetrical intrasellar enhancement, c

SUBMITTER: Kawata M 

PROVIDER: S-EPMC12503844 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature