Adverse Event Following Change in Brachytherapy Plaque-Cleaning Chemicals: A Case Series.

ABSTRACT:

Introduction

The brachytherapy plaques used for uveal melanoma treatment are reused following sterilization processes. Here, we report patients with adverse reaction following a new cleaning procedure for brachytherapy plaques.

Case presentations

The brachytherapy plaque sewn on the outer eyewall would be removed following the delivery of calculated radiation dose. They are reused following standard calibration testing and sterilization processes. From September 2021 to January 2022, 6 patients treated with ruthenium-106 plaque brachytherapy presented with severe unilateral pain, eyelid swelling, and conjunctival injection with hemorrhage 1-2 days following plaque insertion. The surgeons observed a frosted appearance of the plaques in contrast to the normal shiny look during

SUBMITTER: Navaratnam J 

PROVIDER: S-EPMC12503875 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature