Comparative Study of Laparoscopic Hepatectomy, Open Hepatectomy, and Percutaneous Radiofrequency Ablation for Small Hepatocellular Carcinoma: An Ancillary Study of the SURF Trial.

ABSTRACT:

Background

Laparoscopic hepatectomy (LH) for hepatocellular carcinoma (HCC) is increasing. To evaluate the efficacy of LH for small HCC (≤3 tumors within ≤3 cm), we compared short- and long-term outcomes between LH, open hepatectomy (OH), and radiofrequency ablation (RFA) as an ancillary study of the prospective multicenter study "Efficacy of SUrgery vs. Radio Frequency ablation on primary hepatocellular carcinoma" (SURF trial).

Methods

The study population comprised patients enrolled in the SURF trial. Primary endpoints were recurrence-free survival (RFS) and overall survival (OS). Secondary endpoints were short-term outcomes and the relation between tumor conditions and prognosis for each treatment. RFS and OS were adjusted by inverse probability of treatment-weighting ana

SUBMITTER: Masuda T 

PROVIDER: S-EPMC12503888 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature