Identification of copy number variations through whole genome resequencing between Jiuyishan and Hyplus rabbits.

ABSTRACT: Copy number variations (CNVs), which include duplications and deletions of DNA segments, are significant structural variants that play crucial roles in the genetics of complex traits in livestock. High-throughput sequencing technologies enable the systematic identification of structural variants across genomes. However, CNV-based analyses of whole-genome sequencing data in rabbits remain largely unexplored. Herein, we characterized genome-wide CNVs of two rabbit breeds, Jiuyishan rabbit (JY) and Hyplus rabbit (HP), using whole-genome resequencing to elucidate their genetic characteristics and selection signatures. In total, 5,599 CNV regions (CNVRs) were identified between JY and HP, covering 0.98% of the reference genome. To identify selection signatures, we employed variance stabilizing

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12504071 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature