Acute respiratory distress syndrome in patients with cancer: the YELENNA prospective multinational observational cohort study.

ABSTRACT:

Purpose

Acute respiratory failure is the leading reason for intensive care unit (ICU) admission among critically ill patients with cancer. We aimed to describe the clinical characteristics, risk factors, and outcomes of patients with cancer and acute respiratory distress syndrome (ARDS) and to evaluate associations of venovenous extracorporeal membrane oxygenation (ECMO) with outcomes in the subgroup with severe ARDS.

Methods

We conducted a multinational, prospective, observational cohort study of patients with cancer and ARDS in 13 countries in Europe and North America. The primary endpoint was 90-day mortality.

Results

Among 715 included patients, 73.4% had hematologic malignancies and 26.6% solid tumors; 31.2% had undergone hematopoietic stem-cell transplantation (

SUBMITTER: Schellongowski P 

PROVIDER: S-EPMC12504369 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature