Influence of subretinal drusenoid deposit on retinal sensitivity in age-related macular degeneration.

ABSTRACT: This retrospective study aimed to assess the impact of subretinal drusenoid deposit (SDD), also known as reticular pseudodrusen, on retinal sensitivity (RS) in patients with intermediate age-related macular degeneration (iAMD) using microperimetry. Eyes meeting the modified criteria of iAMD, including SDD, and total drusen area greater than 0.50 mm² were included. The presence of SDD, as well as soft drusen (SD), and specific type of SDD (dot or ribbon) were determined through multimodal imaging modalities including fundus photography, fundus autofluorescence, infrared reflectance image and optical coherence tomography. RS was measured using MAIA microperimetry. A total of 302 eyes from 302 patients were analyzed. Patients with SDD were older and predominantly female. Average RS

SUBMITTER: Lim SH 

PROVIDER: S-EPMC12504450 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature