The study of dual-phase ¹⁸F-FDG PET/CT-based models in predicting malignant solitary pulmonary lesions.

ABSTRACT: The morphology of benign and malignant solitary pulmonary lesions sometimes overlaps, making the differentiation difficult. This research aimed to create a radiomics-based prediction model using dual-phase ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography (¹⁸F-FDG PET/CT) for noninvasive classification of these lesions. A total of 132 patients with solitary pulmonary lesions were included. CT, routine PET (PET₁), delayed PET (PET₂) and clinical data were acquired. Five combinations of radiomic features (CT, CT + PET₁, CT + PET₂, CT + PET₁ + PET₂, CT+(PET₂-PET₁)/PET₁) were analyzed. Feature selection used eight methods, and the top ten ranked feature

SUBMITTER: Zhang L 

PROVIDER: S-EPMC12504460 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature