Trends and future projections of alcohol-attributable hepatitis B burden in women of childbearing age (1990-2040): a global analysis.

ABSTRACT:

Introduction

Chronic hepatitis B virus (HBV) infection affects over 254 million people globally, with women of childbearing age (WCBA) facing dual risks of vertical transmission and alcohol-exacerbated disease progression. This study quantifies the alcohol-attributable burden of HBV among WCBA across 204 countries from 1990 to 2021 and projects trends to 2040.

Methods

Data on deaths and Disability-Adjusted Life Years (DALYs) were extracted from the Global Burden of Diseases (GBD) Study 2021. Joinpoint regression and decomposition analyses were used to assess historical trends, while Bayesian Age-Period-Cohort (BAPC) analysis predicted future trends.

Results

Between 1990 and 2021, global deaths showed a significant increase to 1,551.98 (95% UI: 700.34 to 2,707.01), acc

SUBMITTER: Li J 

PROVIDER: S-EPMC12504466 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature