From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.

ABSTRACT:

Background

Respiratory viruses such as rhinovirus and respiratory syncytial virus (RSV) are common triggers of asthma exacerbations in children. The COVID-19 pandemic introduced non-pharmaceutical interventions (NPIs) that altered viral circulation; however, their long-term effects on pediatric asthma outcomes remain unclear.

Objective

To evaluate how the epidemiology and severity of respiratory viral infections in children with asthma changed before, during, and after COVID-19-related NPIs.

Methods

We conducted a cross-sectional analysis of pediatric asthma patients (ages 4-18) with laboratory-confirmed respiratory viral infections from 2018 to 2024 at Arkansas Children's (AC) and AC Northwest (ACNW). Viral detection was performed using the BioFire® Respiratory Panel

SUBMITTER: Jones C 

PROVIDER: S-EPMC12504475 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature