Changes in the vaginal microbiome in female patients with condyloma acuminatum and its impact on persistent HPV infection.

ABSTRACT: Condyloma acuminatum (CA) is one of the most common sexually transmitted diseases, and is characterized by a long incubation period and a high recurrence rate. The vaginal microbiome significantly impacts female reproductive health, influencing susceptibility to human papillomavirus (HPV) infections and related conditions such as CA. However, the role of the vaginal microbiome in the development of CA, especially regarding persistent HPV infection and CA recurrence, remains unclear. We aimed to investigate changes in the vaginal microbiota among female patients with vaginal CA and to determine if disturbances in vaginal flora contribute to persistent HPV infection and CA recurrence. In this study, vaginal swabs were collected from 63 female patients with vaginal CA and 20 healthy females.

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12504535 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature