Sumac (<i>Rhus coriaria L.</i>) Supplementation on High-Sensitivity C-Reactive Protein Concentrations in Adults: A Systematic Review and Dose-Response Meta-Analysis.

ABSTRACT:

Background

Chronic low-grade inflammation is implicated in the development of various metabolic and cardiovascular disorders. Sumac (Rhus coriaria L.) is a medicinal plant with potential anti-inflammatory properties. However, the effects of sumac supplementation on inflammatory biomarkers, particularly high-sensitivity C-reactive protein (hs-CRP), remain controversial.

Objectives

This systematic review and meta-analysis aimed to evaluate the effect of sumac supplementation on hs-CRP concentrations in adults.

Methods

A systematic search was performed in PubMed, Scopus, Web of Science, and the Cochrane Library databases up to February 2025 to identify RCTs examining the impact of sumac supplementation on hs-CRP concentrations. Screening, data extraction, and risk

SUBMITTER: Jazinaki MS 

PROVIDER: S-EPMC12504994 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature