Digital integration of research conduct into clinical care: results of the PROSPECTOR randomised feasibility study.

ABSTRACT:

Objectives

To evaluate the feasibility of conducting a clinically integrated randomised comparative effectiveness trial using digital clinical trial infrastructure within an electronic patient record (EPR).

Design

A mixed-methods, unblinded, feasibility study of digital clinical trial system incorporating testing of two designs of electronic point-of-care randomisation prompt.

Setting

The study was conducted at University College London Hospitals NHS Trust between March and November 2022. The study used a real clinical research question for context, comparing liberal vs restrictive strategies for magnesium supplementation to prevent new-onset atrial fibrillation in critical care.

Participants

Adult patients undergoing elective, non-cardiac surgical procedures e

SUBMITTER: Wilson MG 

PROVIDER: S-EPMC12505030 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature