Examining the relationship between cardiometabolic risk factors and telomere length in women: a systematic review.

ABSTRACT:

Background and objectives

Cardiometabolic syndrome (CMS) poses a significant public health challenge due to its rising prevalence in aging and significant healthcare costs. Recent studies have suggested telomere length (TL), a marker of cellular aging, may be impacted by CMS among women, but comprehensive evidence remains limited. This study aimed to examine the association between CMS risk factors (increased waist circumference [WC], elevated blood pressure, impaired fasting blood glucose, elevated triglycerides, decreased high-density lipoproteins) and TL in women, with consideration of age and race or ethnicity.

Research design and methods

A systematic review was conducted following PRISMA guidelines, with searches across five databases. Thirteen relevant studies publishe

SUBMITTER: Page J 

PROVIDER: S-EPMC12505143 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature