The two sub-genomes of the allotetraploid frog Xenopus laevis are evolving under similar selective pressure in extant populations.

ABSTRACT: The model species Xenopus laevis is an allotetraploid species, whose genome consists of two sub-genomes (the L and S sub-genomes) that were inherited from its parental species. Previous studies comparing the genome of X. laevis with other species of the genus revealed that the L sub-genome was more conserved than the S sub-genome suggesting it has been evolving under stronger purifying selection. However, it remains unclear if this difference reflects evolutionary processes that are still at play in extant populations. To answer this question, we conducted the first genome-wide survey of variation in this species by re-sequencing 44 individuals from its native South African range at ~ 10 × coverage. We generated a dataset of ~ 260M SNPs, which constitutes a valuable resource for the Xenopu

SUBMITTER: Almojil D 

PROVIDER: S-EPMC12505570 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature