Mechanical power normalized to dynamic lung compliance as a predictor of weaning and prognosis in mechanically ventilated patients: a retrospective cohort study.

ABSTRACT:

Background

Predicting weaning outcomes in mechanically ventilated patients remains challenging. While mechanical power (MP) reflects ventilatory load, its accuracy is limited by variability in lung compliance. This study evaluated the predictive value of MP normalized to dynamic lung compliance (Cdyn-MP) for weaning outcomes and prognosis.

Methods

A retrospective observational study was conducted in two ICUs in Jiangsu, China. Patients receiving invasive ventilation ≥ 24 h and undergoing a first spontaneous breathing trial (SBT) via T-tube were included. Patients with accidental extubation, neuromuscular disorders, or without available medical records were excluded. Respiratory mechanics data prior to SBT were retrospectively extracted from medical records. Associations and

SUBMITTER: Yan Y 

PROVIDER: S-EPMC12505575 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature