Clinical outcomes of dolutegravir treatment in people living with HIV in Brazil: protocol for the CODE cohort.

ABSTRACT: The Clinical Outcomes of Dolutegravir Treatment in People Living with HIV in Brazil (CODE) cohort study is a multicenter, prospective, observational study designed to evaluate the safety and efficacy of Dolutegravir (DTG)-based antiretroviral therapy (ART) among people living with HIV across diverse settings in Brazil. With the recent global shift towards DTG as a preferred option for first-line ART, particularly in low- and middle-income countries, there is vital need for comprehensive real-world data to inform its widespread use. CODE aims to fill this knowledge gap by assessing the clinical outcomes of both ART-naïve and ART-experienced patients initiating DTG-based regimens, as well as those who have switched from non-DTG-based ART. The primary objective of this study is to determine t

SUBMITTER: Brites C 

PROVIDER: S-EPMC12505586 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature