First trimester urine glyphosate concentrations and gestational diabetes in nulliparas: a nested case-control study.

ABSTRACT:

Background

Environmental exposures, such as pesticides, during pregnancy have been associated with several adverse pregnancy outcomes, including miscarriage and shorter gestational length at birth. However, their relationship with gestational diabetes (GDM) is uncertain. The objective of this study was to analyze first-trimester urinary herbicide concentrations for their associations with GDM.

Methods

This was a nested case-control study analysis of the Nulliparous Pregnancy Outcomes Study- Monitoring Mothers-to-be (nuMoM2b) study. The study included participants at the three midwestern study sites. We analyzed individuals according to whether they developed GDM. Urinary herbicide concentration at the upper quartile was the exposure of interest. To assess the association of

SUBMITTER: Haas DM 

PROVIDER: S-EPMC12505753 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature