Association of epicardial fat volume index with coronary artery disease phenotypes based on anatomical and functional imaging: a linkage with the severity of coronary artery disease.

ABSTRACT:

Background

Epicardial adipose tissue (EAT) plays an important role in the pathogenesis of coronary artery disease (CAD). The association between EAT and obstructive CAD or myocardial ischemia has been established, but its relationship with CAD phenotypes based on anatomical and functional imaging remains unclear.

Methods

A total of 495 suspected CAD patients who underwent both single-photon emission computed tomography/computed tomography myocardial perfusion imaging (SPECT/CT MPI) and coronary angiography (CAG/CTA) were enrolled in this retrospective study. Epicardial fat volume (EFV) and epicardial fat volume indexed to body surface (EFVi) were measured on non-contrast CT. CAD phenotypes were categorized into 4 groups based on the presence or absence of obstructive CAD (an

SUBMITTER: Wang C 

PROVIDER: S-EPMC12505754 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature