Survival analysis of metachronous bilateral ectopic breast cancer utilizing the SEER database and the pioneering construction of a nomogram model.

ABSTRACT:

Introduction

Metachronous bilateral ectopic breast cancer (MBEBC) is clinically rare, but the incidence has been increasing in recent years and no clear therapeutic guidance or prognostic assessment is available.

Methods

Data on MBEBC patients from the Surveillance, Epidemiology, and End Results (SEER) database were gathered and randomly split into a training set and a validation set at a 7:3 ratio. Independent prognostic risk factors were identified through both univariate and multivariate analyses, and a nomogram was constructed based on these factors to predict survival outcomes.

Results

From the SEER database, we collected data on a total of 8240 patients spanning the years 2005-2015. These patients were then randomly divided into a training set (5768) and a valid

SUBMITTER: Teng L 

PROVIDER: S-EPMC12505798 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature