Prostate specific antigen retesting intervals and trends in England: population based cohort study.

ABSTRACT:

Objective

To characterise the use of the prostate specific antigen (PSA) test in primary care in England.

Design

Population based open cohort study.

Setting

England.

Participants

10 235 805 male patients older than 18 years and registered at 1442 general practices that contributed to the Clinical Practice Research Datalink between 2000 and 2018. Data were linked to the National Cancer Registry, Hospital Episode Statistics, and Office for National Statistics.

Main outcome measures

Population based temporal trends and annual percentage changes were analysed using age standardised PSA testing rates. Mixed effects negative binomial regression models investigated individual patient rate ratios of PSA testing. Linear mixed effects models examined factors assoc

SUBMITTER: Collins KK 

PROVIDER: S-EPMC12505835 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature