Trends in the global burden of childhood meningitis between 1990 and 2021 and projections to 2035: based on the global burden of diseases database 2021.

ABSTRACT:

Objective

This study aimed to assess trends in the incidence, mortality and disability-adjusted life years (DALYs) of meningitis in children aged 0-14 years between 1990 and 2021 worldwide.

Methods

This study analysed the incidence, mortality and DALYs of meningitis in children aged 0-14 years in 204 countries between 1990 and 2021 and used a mixed effects regression model to calculate the average annual percentage change. The Markov chain Monte Carlo method was used to quantify uncertainty (95% uncertainty interval).

Results

In 2021, the global incidence of meningitis in children aged 0-14 years was 66.24 per 100,000, and the mortality rate was 5.59 per 100,000. Between 1990 and 2021, the global incidence decreased by 282.70%, and the mortality rate decreased by 310.

SUBMITTER: Li DD 

PROVIDER: S-EPMC12505982 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature