Performance and potential utility of the BioFire Joint Infection Panel with synovial fluid and joint tissue specimens.

ABSTRACT: The BioFire Joint Infection Panel (BJIP) (bioMérieux) is a rapid sample-to-answer multiplex polymerase chain reaction (PCR) platform for the diagnosis of joint infections. This retrospective study evaluated its performance with synovial fluid and joint tissue specimens from native and prosthetic joints. Joint fluid and tissue specimens received from November 2023 to September 2024 were included. Some specimens were pooled prior to BJIP testing. BJIP results were compared to composite standard laboratory testing (culture, 16S rRNA gene PCR and sequencing [where performed], and concurrent microbiological results for that infection episode). Clinical data were collected (diagnosis, surgical history, antibiotic treatment). Subgroup analysis of native and prosthetic joint specimens was conducte

SUBMITTER: Fox-Lewis S 

PROVIDER: S-EPMC12505999 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature