<i>Gl</i>Slt2 positively regulates <i>Gl</i>Myb-mediated cellulose utilization in <i>Ganoderma lucidum</i>.

ABSTRACT: Fungal degradation of cellulose facilitates the sustainable harnessing of biosphere energy and carbon cycling. Ganoderma lucidum is one of the basidiomycetes with the largest number of hydrolytic enzymes in its genome. The mycelium of G. lucidum degrades cellulose through the production of substantial amounts of cellulase, enabling the absorption of carbon sources and nutrients essential for fruiting body development. The efficiency with which G. lucidum utilizes cellulose is a determinant of its growth rate. In this study, our findings revealed that the mitogen-activated protein kinase GlSlt2 positively modulates cellulase activity and cellulose utilization. Furthermore, a yeast two-hybrid (Y2H) screening library found that GlSlt2 interacts with Gl

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12506057 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature