High risk human papillomavirus versus cytological screening over two rounds in Finnish screening programme for cervical cancer: population based cohort study.

ABSTRACT:

Objective

To compare routine high risk human papillomavirus (hrHPV) screening with cytological screening in two screening rounds in a well established, routine screening programme for cervical cancer.

Design

Population based cohort study.

Setting

Finland's Mass Screening Registry, 2012-22, with diagnostic follow-up examinations until October 2024.

Participants

1 180 491 women participating at least once in cytological test (PAP smear) or hrHPV based cervical cancer screening between 2012 and 2022.

Main outcome measures

Numbers and proportions of attendees, positive routine test results, follow-up screening referrals, colposcopy referrals, and incidence of cervical intraepithelial neoplasia ≥grade 2 (CIN2+) in the first and second hrHPV and cytological sc

SUBMITTER: Turunen IJ 

PROVIDER: S-EPMC12506145 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature