Global, regional and national burden of colon and rectum cancer: a systematic analysis of prevalence, incidence, deaths and DALYs from 1990 to 2021 using data from the Global Burden of Disease Study 2021 with projections to 2036.

ABSTRACT:

Objectives

Colon and rectum cancer, the third most common cancer globally, is a considerable health challenge worldwide. Despite the excellent insights offered by the global burden of disease (GBD) study, comprehensive assessments of colon and rectum cancer remain limited. This study utilises the most recent GBD dataset to examine the impacts of colon and rectum cancer, incorporating contemporary data alongside projections for 2036.

Methods

We analysed data from the 2021 GBD database, focusing on metrics pertaining to colon and rectum cancer: prevalence, incidence, mortality and disability-adjusted life years (DALYs) across 204 countries and territories, classified into 21 GBD regions and five sociodemographic index (SDI) regions. The data analysis encompassed computations o

SUBMITTER: He Y 

PROVIDER: S-EPMC12506162 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature