Head-to-head comparison of the RMI and ADNEX models to estimate the risk of ovarian malignancy: a systematic review and meta-analysis of external validation studies.

ABSTRACT:

Objectives

Assessment of Different NEoplasias in the adneXa (ADNEX) and Risk of Malignancy Index (RMI) are models that estimate the risk of malignancy in ovarian masses based on clinical and ultrasound information. The aim is to perform a meta-analysis of studies that compared the performance of the two models in the same patients ('head-to-head comparison').

Design

Systematic review and meta-analysis.

Data sources

Systematic literature search from publication of ADNEX model (15/10/2014) up to 31/07/2024 in Embase, Web of Science, Scopus, Medline (via PubMed) and EuropePMC.

Eligibility criteria for selecting studies

We included all studies that externally validated the performance of ADNEX (with or without CA125) and RMI on the same data.

Data extraction and

SUBMITTER: Barrenada L 

PROVIDER: S-EPMC12506209 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature