Aedes aegypti strain selected with Bacillus thuringiensis svar. israelensis larvicide for 50 generations remains susceptible and exhibited increased fitness.

ABSTRACT:

Background

Bacillus thuringiensis serovar israelensis (Bti) was the first bacterial larvicide developed for dipteran control. Its insecticidal crystal, composed of protoxins such as Cry11Aa, Cry4Ba, Cry4Aa, and Cyt1Aa, exhibits a selective and complex mode of action and a low potential for resistance development. Most resistance studies have focused on populations from regions where larvicide applications are seasonal, while Aedes aegypti populations in tropical endemic areas may face continuous selection pressure, raising concerns about potential selection of resistance. This study evaluated an Ae. aegypti strain (RecBti), Subjected to strong Bti selection for 50 generations under laboratory conditions, as part of a longitudinal study for assessing in vivo susceptibility to Bti an

SUBMITTER: Menezes HSG 

PROVIDER: S-EPMC12506322 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature