Association between the triglyceride glucose-body mass index and cardiometabolic diseases risk in chronic liver disease: a nationwide cohort study.

ABSTRACT:

Background

The association between cardiometabolic diseases and the triglyceride-glucose-body mass index (TyG-BMI) has been proved. However, the relationship between the TyG-BMI and cardiometabolic complications in chronic liver disease (CLD) patients has not been clearly elucidated. We aimed to investigate whether the TyG-BMI and its trajectory are associated with cardiometabolic comorbidities, especially Cardiovascular-Kidney-Metabolic syndrome (CKM) in patients with CLD.

Methods

We obtained data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020. The exposures were baseline TyG-BMI value at baseline and its change between the first and third waves. The change in TyG-BMI was classified via dynamic time wrapping clustering. The outcomes were

SUBMITTER: Qian T 

PROVIDER: S-EPMC12506333 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature