Insulin-like peptides activate egg formation in the Asian malaria mosquito Anopheles stephensi.

ABSTRACT:

Background

The mosquito family Culicidae diverged into the subfamilies Anophelinae and Culicinae approximately 179 million years ago. Most female mosquitoes are anautogenous and must blood-feed on a vertebrate to produce eggs. Regulation of egg-producing gonotrophic cycles is best understood in the culicine Aedes aegypti. Anopheline mosquitoes encode all of the hormones that regulate gonotrophic cycles in Ae. aegypti, but the processes regulating egg formation may not be fully similar. In this study, we conducted experiments that compared egg formation in Anopheles stephensi to prior findings reported for Ae. aegypti.

Methods

Assays for yolk deposition into oocytes, ovary ecdysteroidogenesis, vitellogenin expression, nutrient storage and oviposition were used to characterize

SUBMITTER: Phipps BL 

PROVIDER: S-EPMC12506429 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature