Micro- and nanoplastics are elevated in femoral atherosclerotic plaques compared with undiseased arteries.

ABSTRACT:

Objective

As plastic production continues to accelerate, the byproducts increasingly fill the environment. Once degraded into micronanoplastics (MNPs), particles may circulate into food, drinking water, or air. Nascent literature has demonstrated MNP bioaccumulation within human tissues, such as the blood, brain, and solid organs. Only recently have MNPs been identified within thrombi and atherosclerotic plaques of diseased blood vessels, and these findings have been associated with adverse clinical outcomes. Data on MNP content in infrainguinal arterial occlusive disease is currently lacking, however. We investigated MNP presence within femoral artery plaques and examined patient clinical variables to characterize their associations in a territory commonly affected by peripheral a

SUBMITTER: Massie PL 

PROVIDER: S-EPMC12506576 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature