Association between night shift work and cardiovascular disease: a systematic review and dose-response meta-analysis.

ABSTRACT:

Background

Shift work, particularly night shift work, has become increasingly prevalent on a global scale and is associated with multiple health issues including type 2 diabetes and cardiovascular diseases (CVD). This study aimed to assess the relationship between night shift work and the incidence and mortality of CVD.

Method

Six electronic databases including PubMed, Embase, Cochrane Library, Web of Science, CINAHL, and Scopus were searched from inception until August 10, 2025. Cohort studies eligible for inclusion addressed the association between night shift work and outcomes of CVD. STATA 18.0 software was used for meta-analysis. The dose-response relationship was estimated using generalized least squares regression, and restricted cubic splines were used to analyze pot

SUBMITTER: Xi J 

PROVIDER: S-EPMC12506678 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature