Clinical Outcomes in Children <5 Years of Age Hospitalized for Respiratory Syncytial Virus, COVID-19 or Influenza in the United States.

ABSTRACT:

Background

This study aimed to compare the clinical burden among young children hospitalized for respiratory syncytial virus (RSV) to coronavirus disease 2019 (COVID-19) or influenza.

Methods

Patients <5 years of age hospitalized for RSV, COVID-19 or influenza between September 2022-August 2024 were selected from the PINC-AI Healthcare Database for retrospective cohort analysis. Hospitalization outcomes included length of stay, supplemental oxygen use, intensive care unit (ICU) admission, invasive mechanical ventilation (IMV) and inhospital death. Weighted robust Poisson regression models estimated risk ratios with 95% confidence intervals comparing RSV to COVID-19 and influenza, with further stratification by age at admission (<1, 1 and 2-4 years).

Results

Among 56,6

SUBMITTER: Andersen KM 

PROVIDER: S-EPMC12506690 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature