Microbiome characterization of a pre-Hispanic man from Zimapan, Mexico: Insights into ancient gut microbial communities.

ABSTRACT: The research of microbiome derived from mummified human remains, coprolites and paleofeces has gained significant interest over several decades, aiming to elucidate the evolution of microbial interactions and shed light on the lifestyles of past populations. In this study, we analyzed the gut microbiome of a pre-Hispanic male individual referred to as the Zimapán man, dated to 936 BP, discovered on the border between Mesoamerica and Aridoamerica. Employing high-throughput 16S rRNA gene sequencing on both the paleofeces and mummified intestinal tissue, we conducted a comprehensive characterization of the Zimapán man's gut microbiome. The bacterial community was described, and a weighted UniFrac-based principal coordinates analysis (PCoA) was performed. The multivariate analysis incorporated

SUBMITTER: Rosas-Plaza S 

PROVIDER: S-EPMC12507283 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature