The integrative analysis of transcriptome and metabolome reveals differences in raw <i>foie gras</i> performance induced by different force-feeding intensities in male Tianfu meat geese.

ABSTRACT: We aimed to explore the influence of different force-feeding intensities on foie gras performance. Geese were force-fed with A (force-feeding four times per day and lasting 28 days) and B (force-feeding 5 times per day and lasting 18 days) at two levels of force-feeding intensities in this study. An integrative analysis of the liver transcriptome, amino acid metabolome, and long-chain fatty acid metabolome was performed. In serum, the levels of blood glucose, insulin, triglyceride (TG), and very low-density lipoprotein (VLDL) of the B group were significantly higher than those of the A group (p < 0.05). The B force-feeding intensity induced more severe steatosis in the goose liver. Transcriptome analysis showed that 948 upregulated differentially expressed genes (DEGs) and 51

SUBMITTER: Teng Y 

PROVIDER: S-EPMC12507551 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature