Association between the aspartate aminotransferase-to-alanine aminotransferase ratio and the reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study.

ABSTRACT:

Background

Studies have shown that the aspartate aminotransferase (AST)/alanine transaminase (ALT) ratio is related to prediabetes, diabetes, and diabetes complications. However, there is limited evidence proving that the AST/ALT ratio is correlated with blood glucose reversal in patients with impaired fasting glucose (IFG). In this study, we analyzed the relationship between the AST/ALT ratio and blood glucose reversal in a large group of Chinese individuals with impaired fasting blood glucose.

Methods

Participants were recruited from the Rich Healthcare Group's physical examinations from 2010 to 2016. Among them, 11,121 Chinese adults were selected for enrollment in this study. Cox proportional hazards regression was used to identify the association between the AST/ALT rat

SUBMITTER: Zhang K 

PROVIDER: S-EPMC12507602 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature