Association between hypothyroidism and metabolic profile in gestational diabetes mellitus.

ABSTRACT:

Introduction

Thyroid hormones exert many effects on glucose metabolism. Gestational diabetes mellitus (GDM) and hypothyroidism during gestation (HG) are the most common gestational endocrinopathies and seem to be associated. We therefore explored in women with GDM whether the presence of HG is associated with a different metabolic profile.

Materials and methods

We included 1,290 pregnant women with GDM [International Association of the Diabetes and Pregnancy Study Group (IADPSG)/World Health Organization (WHO) criteria] and no history of hypothyroidism prior to pregnancy who had a measure of thyroid-stimulating hormone (TSH) and anti-thyroperoxidase antibodies during their hospital stay after GDM diagnosis. Patients with thyrotoxicosis and previous bariatric surgery were exc

SUBMITTER: Pinto S 

PROVIDER: S-EPMC12507628 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature