Predictors and benefits of lipid-lowering therapy initiation after an atherosclerotic cardiovascular event: a retrospective cohort study.

ABSTRACT:

Background

Guidelines recommend lipid-lowering therapy (LLT) after an atherosclerotic cardiovascular disease (ASCVD) event. This study investigated real-world LLT initiation rate and its effect on total mortality in the Lombardy region.

Methods

Individuals aged ≥40 with an ASCVD event between January and September 2022 were identified from Lombardy's administrative data. The prevalence of LLT initiation within 3 months was estimated, and factors influencing treatment initiation were evaluated using multivariate logistic regression (odds ratios [OR] and 95% confidence intervals [95% CI]). One-year post-event mortality was analyzed.

Results

Among 16,025 patients 41.14% did not receive a LLT after an ASCVD event. Treatment initiation was more likely in subjects hospitali

SUBMITTER: Casula M 

PROVIDER: S-EPMC12507633 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature