Diagnostic value and integrated threshold of ESR for diabetic foot osteomyelitis: a systemic review and meta-analysis.

ABSTRACT:

Background

Diabetic foot osteomyelitis (DFO) is a severe complication of diabetic foot infections (DFI). Early and accurate diagnosis is crucial for improving patient outcomes. The erythrocyte sedimentation rate (ESR), a commonly used inflammatory marker, has been controversial regarding its diagnostic value and optimal cutoff values in DFO.

Objective

This study aims to conduct a systematic review and meta-analysis to comprehensively evaluate the diagnostic efficacy of ESR for DFO and to determine an optimal pooled cutoff value for the marker.

Methods

A systematic search of PubMed, EMBASE, Cochrane Library, OVID, and the Wanfang database was conducted for literature related to ESR in the diagnosis of DFO, with the search period extending through March 2025. The Qualit

SUBMITTER: Liu L 

PROVIDER: S-EPMC12507639 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature