Global burden of multidrug-resistant tuberculosis in children and adolescents.

ABSTRACT:

Objectives

Multidrug-resistant tuberculosis (MDR-TB) has become a major global public health issue, which has worsened over time owing to changes in disease-related trends. This study aimed to determine global trends in MDR-TB among children and adolescents for strategic health planning.

Methods

A secondary analysis was performed on MDR-TB burden among children and adolescents (<20 years) at the global, regional, and national levels based on sociodemographic index (SDI) quintiles from 1990 to 2019, using the Global Burden of Disease (GBD) 2019 database.

Results

In 2019, 67,710.82 (95% uncertainty interval [UI]: 38,823.61 to 110,582.03) incidents of MDR-TB were reported among children and adolescents aged <20 years worldwide. The global incidence rate has increased fro

SUBMITTER: Zhong Y 

PROVIDER: S-EPMC12507668 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature