Mathematical correction of the effects of storage time and gas contamination on blood sample measurements.

ABSTRACT:

Objective

Analysis delay and gas contamination can affect the accuracy of blood measurements. This study uses a mathematical model of blood acid-base chemistry and gas in the sample tubes to calculate values of pH, partial pressures of carbon dioxide (pCO₂), partial pressure of oxygen (pO₂), oxygen saturation in whole blood (SO₂), glucose, and lactate at sample time from measurements with delayed analysis and gas contamination.

Methods

Data were analyzed from two published studies. Study 1: Samples were obtained from 30 critically ill patients in standard blood gas syringes and analyzed after 0, 36, 54, 72, 90, 108, 126, 144, 162, and 180 min. Study 2: Samples were taken from 20 healthy participants in standard blood gas syringes and vacuum t

SUBMITTER: Nevirian B 

PROVIDER: S-EPMC12507878 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature