Global, regional, and national total burden related to hepatitis B and attributable risk factors in adults aged 65 years and older from 1990 to 2021 and projection to 2030.

ABSTRACT:

Background

Hepatitis B virus and its complications remain a major global public health threat. This study aimed to assess the global, regional, and national trends of total burden related to hepatitis B among older adults aged ≥65 years from 1990 to 2021 and predict trend to 2030.

Methods

Drawing upon the Global Burden of Diseases (GBD) 2021, we obtained the data on incidence, prevalence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021, categorized by sex, age, and socio-demographic index (SDI). Associations of. these metrics and SDI were analyzed. Secular trends were evaluated employing average annual percentage changes (AAPC) and joinpoint regression, with future trajectories estimated through 2030 using the Bayesian age-period-cohort (BAPC) model.<

SUBMITTER: Gao L 

PROVIDER: S-EPMC12507896 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature