Biofilm-inhibiting ZnO@Eggshell nanocomposites: green synthesis, characterization, and biomedical potential.

ABSTRACT: This study explored the eco-friendly synthesis, characterization, optimization, and biomedical potential of zinc oxide-eggshell (ZnO@ES) nanocomposites using Althaea officinalis flower extract. HPLC analysis identified pink flower extract as the highest in quercetin (88.452 ppm), making it the optimal choice for synthesis. UV-Vis spectroscopy confirmed ZnO nanostructures (384 nm peak), while characterization analyses using different spectroscopic and microscopic techniques validated their successful incorporation within the eggshell matrix. The hemocompatibility of ZnO@ES nanocomposites was assessed through hemolysis tests, which demonstrated low hemolytic activity (<5%), ensuring blood compatibility. Antimicrobial assays against Escherichia coli, Staphylococcus aureus, Pseudomonas aerugin

SUBMITTER: Sensoy Gun B 

PROVIDER: S-EPMC12507985 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature