Temporal and Spatial Trends in the Global Burden of Acne Vulgaris Among Women of Reproductive Age: A Comprehensive Analysis and Forecast From 1990 to 2040.

ABSTRACT:

Background

Acne is a common, multifactorial skin condition with significant psychosocial and public health impacts. However, its burden among reproductive-age women remains underexplored.

Methods

Using Global Burden of Disease (GBD) 2021 data, we analyzed acne incidence, prevalence, and disability-adjusted life years (DALYs) in females aged 15-49 across 204 countries (1990-2021). Trends were assessed via age-standardized rates and estimated annual percentage change (EAPC). Decomposition and inequality analyses identified contributing factors. Bayesian age-period-cohort (BAPC) modeling projected trends to 2040.

Results

From 1990 to 2021, acne incidence, prevalence, and DALYs rose by 34%, 38%, and 37%, respectively. The greatest increases occurred in low-socio-demograph

SUBMITTER: Yan J 

PROVIDER: S-EPMC12508705 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature