Characteristics and outcome of patients with brain metastases from colorectal cancer.

ABSTRACT:

Background

Despite a generally poor prognosis of patients with brain metastases of colorectal cancer (CRC-BM), local treatment of BM might be beneficial in selected patients. The aim of this study was to characterize patient and clinicopathological characteristics of CRC-BM and to identify patients who benefit most from local treatment of CRC-BM.

Methods

In this retrospective cohort study, clinicopathological characteristics, including treatment response and survival, were collected from 100 patients who were treated for CRC-BM at the Netherlands Cancer Institute between 2001 and 2021. All analyses were performed using SPSS.

Results

Median overall survival (OS) from CRC diagnosis and diagnosis of BM was 47.3 and 5.2 months, respectively. Median brain metastasis-free i

SUBMITTER: van den Borg R 

PROVIDER: S-EPMC12508748 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature