Decline in Type 1 Diabetes in Young Children After Rotavirus Vaccination: Data From 8 Countries.

ABSTRACT:

Introduction

Vaccination for rotavirus has been a component of national immunization programs in more than 100 countries, principally intended to decrease hospitalizations and deaths from gastroenteritis in young children. Rotavirus is a major cause of gastroenteritis in infants but can additionally result in apoptosis of pancreatic cells and hyperglycemia. Therefore, it is suspected to be a contributor to Type 1 diabetes mellitus. The purpose of this investigation was to examine whether the incidence of Type 1 diabetes in young children decreased after a rotavirus vaccination program was introduced.

Methods

Publications were assembled with country-specific incidence rates of Type 1 diabetes in children aged <5 years. Data regarding the introduction of national rotavirus vac

SUBMITTER: Rogers MAM 

PROVIDER: S-EPMC12508837 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature