High-Accuracy Quantitative Nuclear Magnetic Resonance Using Improved Solvent Suppression Schemes.

ABSTRACT: Quantitative nuclear magnetic resonance (qNMR) has contributed to reliable and accurate measurements of organic compounds enabling quantitation even when no standards of the specific compounds are available. Such high-accuracy determinations are critical across the field of analytical chemistry, with the advances in qNMR being of utmost importance in the production of reference standards for a range of organic compounds. The ability to perform these accurate measurements in the presence of natural isotopic abundance solvents is important for increasing throughput and expanding the number of applications that benefit. In this work, we have assessed several pulse sequences for solvent suppression. The limitations of NMR acquisitions in the presence of large solvent signals and solvent suppre

SUBMITTER: Garrido BC 

PROVIDER: S-EPMC12509184 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature