Exercise-Induced Changes in Knee Cartilage In Vivo: Comparing MRI Sequences.

ABSTRACT: The purpose was to assess the agreement in measures of acute knee cartilage thickness and composition change after loading in clinical knee osteoarthritis (OA) between two magnetic resonance imaging (MRI) acquisition approaches: (1) single sequence approach using quantitative double-echo in steady-state (qDESS), which allows simultaneous morphological and compositional scanning, versus (2) multi-sequence approach that captures morphology (fast spoiled gradient recalled (FSPGR) or qDESS) and composition (multi-echo spin echo (MESE)) separately. Twenty adults with clinical knee OA participated. 3T MR scans were acquired before and immediately after a 25-min treadmill walk at a standardized speed. Changes in knee cartilage thickness and T2 were assessed. Pre-activity, strong agreement was obs

SUBMITTER: Ivanochko NK 

PROVIDER: S-EPMC12509249 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature