Antioxidant Activity of SiO₂@{Sericin} Hybrids: A Comparable OH-Radical and DPPH-Radical Scavenging Study.

ABSTRACT: A new class of hybrid materials was developed via covalent grafting of sericin, a silk-derived protein, onto SiO₂ particles to assess their antioxidant properties. Two variants of SiO₂@sericin hybrids were synthesized, with 10% ({SiO₂@sericin_10}) or 20% ({SiO₂@sericin_20}) sericin loadings. An in tandem analysis of their antioxidant efficiency was performed against OH and DPPH radicals. The experimental results demonstrate that the {SiO₂@sericin} hybrids exhibit significantly enhanced antioxidant activity compared with sericin in aqueous solution. Specifically, 1 g of the {SiO₂@sericin_10} hybrid quenches 308 μmol of DPPH radicals and 120 μmol of ^●OH, whereas aqueous sericin in solution quenched only 85 μm

SUBMITTER: Theofanous A 

PROVIDER: S-EPMC12509319 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature