Association between oxidative balance score and allergic rhinitis in American adults: a cross-sectional study.

ABSTRACT:

Background

Oxidative stress has been implicated in the development of allergic rhinitis (AR), yet its population-level impact using composite oxidative metrics remains underexplored. This study aimed to investigate the association between the oxidative balance score (OBS), a composite indicator of pro- and antioxidant exposures, and AR in U.S. adults.

Methods

We analyzed data in the 2005-2006 NHANES. An OBS, comprising 16 dietary and 4 lifestyle factors, was calculated and analyzed as both a continuous variable and by quartiles. Associations with AR were assessed using multivariable logistic regression and restricted cubic spline (RCS) models. Survey-weighted analyses were additionally performed to account for the complex sampling design and assess national representativenes

SUBMITTER: Tian Y 

PROVIDER: S-EPMC12509687 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature